S. J. Booker

FDX1 regulates cellular protein lipoylation through direct binding to LIAS.

This study identifies FDX1 as a direct regulator of protein lipoylation by binding to LIAS, essential for cell survival under low glucose conditions.

How synonymous mutations alter enzyme structure andfunction over long time scales

This paper shows that synonymous mutations alter enzyme function over time by causing misfolded, entangled protein states that reduce catalytic activity.