Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies
L. Goldstein, Y.-J. J. Chen, J. Wu, S. Chaudhuri, Y.-C. Hsiao, K. Schneider, K. H. Hoi, Z. Lin, S. Guerrero, B. S. Jaiswal, S. Jeremy, A. Antony, k. B. Pahuja, D. Seshasayee, Z. Modrusan, , S. Seshagiri
The paper uses scBCR-seq to analyze B-cell repertoires and identifies antigen-reactive antibodies with high accuracy.
bioRxiv · Jun 6, 2019Immunology