Tackling emerging artemisinin resistance by modulating the defensive oxido-reductive mechanism of human malaria parasite by repurposing nitrofurantoin
S. Shafi, S. Gupta, R. Jain, R. Shoaib, A. Munjal, P. Maurya, A. K. Najmi, S. Singh
This paper evaluates the anti-malarial potential of Nitrofurantoin against sensitive and resistant Plasmodium falciparum strains, finding synergistic effects with artemisinin and enhanced oxidative stress.
bioRxiv · Apr 18, 2023 · PreprintPharmacology & Toxicology