Harnessing β-Lactam Antibiotics for Illumination of the Activity of Penicillin-Binding Proteins in Bacillus subtilis
S. Sharifzadeh, F. Dempwolff, D. B. Kearns, E. E. Carlson
This study identifies β-lactam antibiotics that selectively inhibit specific penicillin-binding proteins (PBPs) in Bacillus subtilis and reveals PBP3 activity patterns using activity-based probes.
bioRxiv · Dec 19, 2019Microbiology