Author

S. Stoilova-McPhie

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

D. Finley· 1 shared S. Zhang· 1 shared W. L. Wang· 1 shared X. Li· 1 shared Y. Dong· 1 shared Y. Lu· 1 shared Y. Mao· 1 shared Y. Zhu· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperBiochemistry

D. Finley

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1 paper

Recent·Most cited

BiochemistrybioRxivSep 16, 2018

Visualizing ATP-dependent substrate-processing dynamics of the human 26S proteasome at near-atomic resolution

Y. Dong, S. Zhang, Z. Wu…·Y. Mao

The paper presents cryo-EM structures of the human 26S proteasome in seven conformational states during polyubiquitylated protein degradation, revealing dynamic substrate-proteasome interactions and ATP hydrolysis mechanisms.

DOI 10.1038/s41586-018-0736-4

humancryo-EM

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