Enhancer evolution as a driving force for lineage-specific paralog usage in the central nervous system.
C. Fujimori, K. Sugimoto, M. Ishida, C. Yang, D. Kayo, S. Tomihara, K. Sano, Y. Akazome, Y. Oka, S. Kanda
The paper investigates how enhancer evolution drives lineage-specific paralog usage in hypophysiotropic GnRH neurons across vertebrates, finding that enhancer loss, not regulatory changes, caused paralog role division.
bioRxiv · Apr 20, 2023Evolutionary Biology