Improved Isolation of Extracellular Vesicles by Removal of Both Free Proteins and Lipoproteins
D. Ter-Ovanesyan, T. Gilboa, B. Budnik, A. Nikitina, S. Whiteman, R. Lazarovits, W. Trieu, D. Kalish, G. M. Church, D. R. Walt
The paper develops a method to improve EV isolation by quantitatively measuring and removing free proteins and lipoproteins using Simoa assays and chromatography.
bioRxiv · Jan 20, 2023Bioengineering