Efficient internalization of poly(benzyl malate) and poly(ethylene glycol)-b-poly(benzyl malate) copolymer based nanoparticles by human hepatic HepaRG cells and macrophages : Impact of nanoparticle functionalization by GBVA10-9 peptide on cell uptake.
Hanadi Nahas, Saad Saba, Perla METLEJ, Catherine Ribault, Élise Vène, Nicolas Lepareur, Sandrine Cammas‐Marion, Pascal Loyer
This study compares nanoparticle uptake by HepaRG cells and macrophages, showing PMLABe-based NPs are efficiently internalized while PEGylated variants show reduced uptake, and GBVA10-9 peptide does not significantly affect uptake.
bioRxiv · Jul 26, 2024 · PreprintCell Biology