E. coli populations in unpredictably fluctuating environments evolve to face novel stresses through enhanced efflux activity
Shraddha Madhav Karve, Sachit Daniel, Yashraj Chavhan, Abhishek Anand, Somendra Singh Kharola, Sutirth Dey
This study shows that E. coli populations evolving in fluctuating environments develop enhanced efflux activity, leading to increased fitness in novel stress conditions without evolving hypermutators.
bioRxiv · Apr 8, 2015Evolutionary Biology