A rationally designed neuraminidase immunogen elicits humoral responses to a conserved viral site
Rachel Hecht, Faez Amokrane Nait Mohamed, Shiyu Zhang, Shaun D. Rawson, Saeyoung E. Lee, Connor L. Murphy, Dana N. Thornlow, Larance Ronsard, Timothy M. Caradonna, Daniel Lingwood, Aaron G. Schmidt
A hyperglycosylated influenza neuraminidase immunogen reshapes humoral immunity and elicits antibodies targeting a conserved tetramer-interface epitope.
bioRxiv · Aug 17, 2026 · PreprintImmunology