Determining organ size through growth rate dependent negative feedback without sensing size.
Carmen M A Coelho, Abhishek Sharma, Jaya Anusha Rachamadugu, Varshitha Prabhakhar, Saher Chawla
This paper proposes a model for organ size determination in Drosophila imaginal discs where growth rate-dependent negative feedback, not size sensing, regulates size restoration during growth.
bioRxiv · Jun 11, 2026 · PreprintDevelopmental Biology