Author

Sam Barkal

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1

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Approach:Bayesian inference· 1 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Christopher A. CassaiD· 1 shared David Benjamin AscheriD· 1 shared Guillaume LettreiD· 1 shared Jayoung RyuiD· 1 shared Lara Brown· 1 shared Luca PinelloiD· 1 shared Manuel TognoniD· 1 shared Martin JankowiakiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Christopher A. CassaORCID

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1 paper

Recent·Most cited

Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification

Jayoung Ryu, Sam Barkal, Tian Yu, Martin Jankowiak, Yunzhuo Zhou, Matthew Francoeur, Quang Vinh Phan, Zhijian Li, Manuel Tognon, Lara Brown, Michael I. Love, Vineel Bhat, Guillaume Lettre, David Benjamin Ascher, Christopher A. Cassa, , Luca Pinello

This paper improves variant effect quantification in base editing screens by integrating genotypic and phenotypic data using a Bayesian network called BEAN.

Nature Genetics · Apr 24, 2024Peer-reviewedGenetic & Genomic Medicine