Martin Jankowiak

CRISPR-CLEAR maps regulatory elements at nucleotide resolution by directly assessing genotype-phenotype effects through targeted sequencing of CRISPR-introduced alleles.

This paper improves variant effect quantification in base editing screens by integrating genotypic and phenotypic data using a Bayesian network called BEAN.

This paper introduces BVAS, a Bayesian method to infer fitness-associated mutations in SARS-CoV-2 using 6.9 million genomes, identifying key mutations and epistatic interactions.