DNA methylation modulates transcription factor occupancy chiefly at sites of high intrinsic cell-type variability
Matthew Maurano T, Hao Wang, Sam John, Anthony Shafer, Theresa Canfield, Kristen Lee, John A Stamatoyannopoulos
This study shows DNA methylation primarily stabilizes transcription factor binding at sites with high cell-type variability, not broadly repressing TF occupancy.
bioRxiv · Feb 27, 2014 · PreprintGenomics