Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature
Samantha M Thomas, Courtney Kagan, Bryan J Pavlovic, Jonathan Burnett, Kristen Patterson, Jonathan K Pritchard, Yoav Gilad
This study shows that reprogramming LCLs to iPSCs recovers donor-specific gene expression signatures, suggesting iPSCs better reflect genetic influences on gene regulation than LCLs.
PLOS Genetics · May 7, 2015Peer-reviewedGenomics