Monounsaturated fatty acid biosynthesis is critical for streptococcal envelope homeostasis and stress tolerance
Jonathon L. Baker, Jonah Tang, Mingzhe Guo, Felipe Fabrício Farias da Silva, Matthew Barbisan, Molly Burnside, Kaitlin Crofton, Samantha Williams, Saarin Rao, Michelle Lee, Sadie G. Drucker, Daniel Kim, Dustin L. Higashi, Justin Merritt, Yujiro Hirose, , Victor Nizet
This study shows that monounsaturated fatty acid biosynthesis is essential for streptococcal growth, stress tolerance, and virulence, with species-specific effects on pathogenesis.
Journal of Bacteriology · Aug 7, 2026Peer-reviewedMicrobiology