Author

Samira Sadeghi

University of Toronto

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Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A.M. EdwardsiD· 1 shared Douglas W. HoustoniD· 1 shared Rachel HardingiD· 1 shared Rebeka Cataldo de Oliveira FantiiD· 1 shared Renu ChandrasekaraniD· 1 shared Yang‐Nim Park· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperNeuroscience

A.M. EdwardsORCID

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1 paper

Recent·Most cited

Novel monoclonal antibodies against the C-terminal HEAT domain of Huntingtin

Yang‐Nim Park, Rebeka Cataldo de Oliveira Fanti, Samira Sadeghi, Renu Chandrasekaran, A.M. Edwards, Rachel Harding, Douglas W. Houston

The paper develops and validates novel monoclonal antibodies targeting the C-terminal HEAT domain of huntingtin, showing they detect full-length HTT regardless of polyglutamine length or HAP40 interaction.

Journal of Huntington s Disease · Mar 5, 2026Peer-reviewedNeuroscience