Development of a long-read high-throughput chromatin conformation capture method for evaluating both cis and trans interactions between integrated Hepatitis B Virus and host genomes.
Yih‐Ping Su, Joshua P. Earl, Azad A. Ahmed, Bhaswati Sen, Samuel Czerski, Garth D. Ehrlich
The paper develops a long-read Hi-C method to study 3D interactions between integrated HBV DNA and host genomes, improving sensitivity and specificity for analyzing these interactions.
bioRxiv · Oct 21, 2025 · PreprintGenomics