CD4+ T cells recruit, then engage macrophages in cognate interactions to clear Mycobacterium tuberculosis from the lungs.
Samuel H. Becker, Christine E. Ronayne, Tyler D. Bold, Marc K. Jenkins
This study shows CD4+ T cells recruit macrophages to clear Mtb by MHCII-mediated cognate interactions, not IFN-{gamma}, promoting glycolysis in macrophages for bacterial control.
PLoS Pathogens · Jun 9, 2025Peer-reviewedImmunology