Deficiency of cyclin-dependent kinase-like 5 causes spontaneous epileptic seizures in neonatal mice
Wenlin Liao, Kun-Ze Lee, San-Hua Su, Yuju Luo
This study identifies spontaneous seizures in CDKL5-deficient mice, showing reduced phosphorylation of K+/Cl- co-transporter 2 and highlighting the translational value of CDD mouse models.
bioRxiv · Mar 9, 2020 · PreprintNeuroscience