Dietary Microplastics Engage Gut Mechanosensory-Endocrine Signaling and Disrupt Bone Homeostasis
Aaron S. Romero, Sumira Phatak, Sanchiti Patil, Hamid Y. Dar, Jaclyn A. Rivas, Olufunmilola Oyebamiji, Brianna B. Maes, Siem S. Goitom, Crystal Madera Enriquez, Jazmin Orozco, Cristina N. Coffman, Ruixuan Liu, Julie In, Matthew J. Campen, Kel Cook, , Eliseo F. Castillo
This study shows that dietary microplastics alter gut neuroendocrine signaling and disrupt bone health in mice, with effects dependent on sex and diet.
bioRxiv · Jun 26, 2026 · PreprintPhysiology