Phosphoproteomics implicates glutamatergic and dopaminergic signalling in the antidepressant-like properties of the iron chelator deferiprone
Volkan Uzungil, Sandra Luza, Carlos Opazo, Isaline Mees, Shanshan Li, Ching‐Seng Ang, Nicholas A. Williamson, Ashley Ian Bush, Anthony John Hannan, Thibault Renoir
The paper uses phosphoproteomics to identify molecular changes in the prefrontal cortex of 5-HTT KO and WT mice after deferiprone treatment, implicating glutamatergic and dopaminergic signaling in its antidepressant-like effects.
Neuropharmacology · Jan 4, 2024Peer-reviewedBioinformatics