Two distinct functional axes of positive feedback-enforced PRC2 recruitment in mouse embryonic stem cells
Matteo Perino, Guido van Mierlo, Chet Hong Loh, Sandra M.T. Wardle, Dick W. Zijlmans, Hendrik Marks, Gert Jan C. Veenstra
The paper investigates how PRC2 sub-complexes recruit to target genes in mESCs, revealing mutual reinforcement and feedback mechanisms between PRC2.1, PRC2.2, and PRC1.
Stem Cell Reports · Aug 6, 2020Peer-reviewedMolecular Biology