Cryo-EM Structure of the relaxosome, a complex essential for bacterial mating and the spread of antibiotic resistance genes
Sunanda Margrett Williams, Sandra Raffl, Sabine Kienesberger, Aravindan Ilangovan, Ellen L. Zechner, Gabriel Waksman
The paper presents the cryo-EM structure of the relaxosome from the F plasmid in two functional states, revealing conformational changes and interaction hubs involved in bacterial conjugation.
Nature Communications · May 27, 2025Peer-reviewedMicrobiology