Defective Integrator activity shapes the transcriptome of patients with multiple sclerosis
Yevheniia Porozhan, Mikkel Carstensen, Sandrine Thouroude, Mickaël Costallat, Christophe Rachez, Éric Batsché, Thor Petersen, Tove Christensen, Christian Muchardt
The paper identifies reduced CBX5 expression and impaired Integrator activity in MS patients, linking them to transcriptomic alterations and disease progression.
Life Science Alliance · Jul 19, 2024Peer-reviewedGenomics