Santiago Schnell

On the estimation errors of KM and V from time-course experiments using the Michaelis-Menten equation

The paper analyzes the conditions under which the Michaelis-Menten equation can accurately estimate KM and V from progress curve data, showing that initial substrate and enzyme concentrations must be carefully controlled.

Quantitative proteome-based guidelines for intrinsic disorder characterization

The paper establishes quantitative proteome-based guidelines for assessing intrinsic disorder in proteins using non-parametric statistics and multiple disorder prediction algorithms across ten eukaryotic proteomes.

On the validity and errors of the pseudo-first-order kinetics in ligand-receptor binding

The paper analyzes the validity and errors of pseudo-first-order kinetics in ligand-receptor binding, showing that the two interpretations of validity are distinct and can lead to large errors in kinetic constant estimation.

Estimation of the lag time in a subsequent monomer addition model for fibril elongation

The paper estimates lag time in a monomer addition model for fibril elongation using rate equations, revealing causal connectivity between intermediates and differences in lag phase detection across assays.

Varing chemical equilibrium gives kinetic parameters

The paper introduces a method to determine kinetic parameters of a chemical reaction by analyzing chemical equilibrium rather than dynamic behavior.