Age, Sex and Alzheimer's disease: A longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer's patients
Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur
This study shows that male and female 3xTg-AD mice have different disease trajectories, with males showing more inflammation and females more neuropathology, mirrored in human Alzheimer's patients.
Alzheimer s Research & Therapy · Jun 22, 2024Peer-reviewedNeuroscience