NeuroscienceAlzheimer s Research & TherapyPeer-reviewed
Age, Sex and Alzheimer's disease: A longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer's patients
Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain…·Arti B Gaur
This study shows that male and female 3xTg-AD mice have different disease trajectories, with males showing more inflammation and females more neuropathology, mirrored in human Alzheimer's patients.
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