TDP-43 pathology in Drosophila induces glial-cell type specific toxicity that can be ameliorated by knock-down of SF2/SRSF1.
Sarah Krupp, Isabel Hubbard, Oliver H. Tam, Molly Hammell, Josh Dubnau
This study shows that TDP-43 pathology in Drosophila glial cells causes systemic toxicity, which can be reduced by knocking down SF2/SRSF1.
PLoS Genetics · Sep 25, 2023Peer-reviewedNeuroscience