miRNA-mediated control of gephyrin synthesis drives sustained inhibitory synaptic plasticity
Theresa M. Welle, Dipen Rajgor, Dean J. Kareemo, Joshua D Garcia, Sarah M Zych, Sarah E. Wolfe, Sara E. Gookin, Thyandra A. Martinez, Mark L. Dell’Acqua, Christopher Ford, Matthew J. Kennedy, Katharine R. Smith
This study identifies miR153 as a regulator of gephyrin translation during inhibitory long-term potentiation, showing its downregulation enables synaptic strengthening.
EMBO Reports · Sep 18, 2024Peer-reviewedNeuroscience