Global Profiling of Remodeled Subcellular Structures Due to Drug Treatment and Disease
Rachel A. Victor, Jesse J. Altemus, Michelle A. Lay, Sarah N. Shepherd, Valery F. Thompson, Mozani Zianti, Marco Padilla‐Rodriguez, Austin A. Lipinski, Ghassan Mouneimne, Paul R. Langlais, Jacob C. Schwartz
The paper uses SEC-MS with crosslinking to analyze global changes in subcellular structures in Ewing sarcoma cell lines and after drug treatment, identifying effects on splicing, mitochondria, nucleoli, and peroxisomes.
Molecular and Cellular Biology · Aug 3, 2026Peer-reviewedBiochemistry