PTE, a novel module to target Polycomb Repressive Complex 1 to the Cyclin D2 oncogene.
Sarina R. Cameron, Soumyadeep Nandi, Tatyana G. Kahn, Juan Ignacio Barrasa, Per Stenberg, Yuri B. Schwartz
The paper identifies a PRC1 targeting element (PTE) and CpG-island that together form a Polycomb Response Element for the CCND2 oncogene, showing their role in coordinating PRC1 and PRC2 recruitment.
Journal of Biological Chemistry · Aug 1, 2018Peer-reviewedMolecular Biology