METTL16 promotes taxane resistance in Triple-Negative Breast Cancer through m6A-dependent translational upregulation of ABCB1
Elise G. Holvey-Bates, Jesse A. Coker, Daniel J. Lindner, Anchal Agarwal, Anand Bhushan, Yvonne Parker, Hannah L. Gilmore, Anton A. Komar, George Robert Stark, Sarmishtha De
This study identifies METTL16 as a driver of taxane resistance in TNBC by enhancing ABCB1 translation via m6A modification, showing its therapeutic potential.
bioRxiv · Mar 13, 2026 · PreprintCancer Biology