Inhibition of KDM1A activity restores adult neurogenesis and improves hippocampal memory in a mouse model of Kabuki syndrome
Li Zhang, Genay O.W. Pilarowski, Emilio Merlo Pich, Atsushi Nakatani, John Dunlop, Rina Baba, Satoru Matsuda, Masaki Daini, Yasushi Hattori, Shigemitsu Matsumoto, Mitsuhiro Ito, Haruhide Kimura, Hans Tomas Bjornsson
The paper shows that inhibiting KDM1A activity rescues adult neurogenesis and hippocampal memory defects in a mouse model of Kabuki syndrome.
Molecular Therapy — Methods & Clinical Development · Feb 21, 2021Peer-reviewedGenetics