Wnt signaling couples G2 phase control with differentiation during hematopoiesis
Lauren M. Goins, Juliet R. Girard, Bama Charan Mondal, Sausan Buran, Chloe C. Su, Ruby Tang, Titash Biswas, Utpal K. Banerjee
This study shows that Wnt6/EGFR signaling controls progenitor growth, proliferation, and differentiation by regulating G2 phase and cell-cycle exit through both β-catenin-dependent and -independent pathways in Drosophila hematopoiesis.
bioRxiv · Jun 29, 2023 · PreprintDevelopmental Biology