Computational design and evaluation of optimal bait sets for scalable proximity proteomics
Vesal Kasmaeifar, Saya Sedighi, Anne‐Claude Gingras, Kieran R. Campbell
The paper develops GENBAIT, a genetic algorithm-based tool to optimize bait selection for BioID experiments, reducing bait numbers while maintaining dataset coverage and structure.
Nature Communications · Oct 22, 2025Peer-reviewedBioinformatics