Post-GWAS functional analyses of CNTNAP5 suggests its role in glaucomatous neurodegeneration
Sudipta Chakraborty, Jyotishman Sarma, Shantanu Saha Roy, Sukanya Mitra, Sayani Bagchi, Sankhadip Das, Sreemoyee Saha, Surajit Mahapatra, Samsiddhi Bhattacharjee, Mahua Maulik, Moulinath Acharya
This study identifies CNTNAP5 as a candidate gene for glaucomatous neurodegeneration through zebrafish knockdown experiments showing retinal degeneration and behavioral changes.
bioRxiv · Mar 14, 2024 · PreprintGenetics