Samsiddhi Bhattacharjee

This study identifies pleiotropic variants and trait-specific susceptibility variants using GWAS data from 116 traits, revealing widespread pleiotropy and unique genetic contributions to specific traits.

This study identifies CNTNAP5 as a candidate gene for glaucomatous neurodegeneration through zebrafish knockdown experiments showing retinal degeneration and behavioral changes.

This study uses whole exome sequencing in families with multiple affected individuals to identify rare variants in genes associated with both Mendelian and complex neuropsychiatric syndromes.

The paper introduces a regression-based framework to enhance GWAS power by incorporating pathway knowledge, showing improved SNP detection while controlling type-1 error.