The Effect of Resistance Training Volume on Individual-Level Skeletal Muscle Adaptations: A Novel Replicated Within-Participant Unilateral Trial
Zac P. Robinson, James Steele, Eric R. Helms, Eric T. Trexler, Michael E. Hall, Chun-Jung Huang, Joshua C. Pelland, Jacob F. Remmert, Seth R. Hinson, Scott A. Mikula, Alexandre A. Hamaïde, Michael Christopher Zourdos
This study investigates how resistance training volume affects skeletal muscle adaptations and inter-individual response variation using a within-participant design, finding detectable benefits for hypertrophy but not strength, and limited evidence of true inter-individual differences.
bioRxiv · Jul 24, 2025 · PreprintPhysiology