Exact mapping of Illumina blind spots in the Mycobacterium tuberculosis genome reveals platform-wide and workflow-specific biases
Samuel J. Modlin, Cassidy Robinhold, Christopher Morrissey, Scott N. Mitchell, Sarah M. Ramirez-Busby, Tal Shmaya, Faramarz Valafar
The paper identifies Illumina sequencing biases in M. tuberculosis genomes across seven workflows, revealing blind spots and proposing strategies to mitigate them.
Microbial Genomics · Jan 27, 2021Peer-reviewedBioinformatics