Author

Samuel J. Modlin

San Diego State UniversityORCID 0000-0002-7674-305XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Research Focus:gene regulatory network inference· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Faramarz ValafariD· 3 shared Cassidy RobinholdiD· 2 shared Sarah M. Ramirez-BusbyiD· 2 shared Afif ElghraouiiD· 1 shared Alyssa M. ZlotnickiiD· 1 shared Anthony D. BaughniD· 1 shared Calvin Kim· 1 shared Carmela K. Chan· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersGenomics

Faramarz ValafarORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintNov 23, 2021

Rare alternative second line injectable drug resistance markers identified by gene-wise genome wide association in M. tuberculosis with unexplained resistance

Derek Conkle-Gutierrez, Calvin Kim, Sarah M. Ramirez-Busby…·Faramarz Valafar

The paper identifies rare alternative resistance markers in M. tuberculosis using gene-wise genome-wide association, uncovering novel associations with second-line injectable drug resistance.

1 citation

whole-genome sequencingstatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintJun 30, 2021

Structure-aware M. tuberculosis functional annotation uncloaks resistance, metabolic, and virulence genes

Samuel J. Modlin, Afif Elghraoui, Deepika Gunasekaran…·Faramarz Valafar

The paper updates functional annotations for Mycobacterium tuberculosis genes using literature curation and structural modeling, identifying resistance, metabolic, and virulence genes.

3 citations

humanwhole-genome sequencing

𝕏 PostBluesky

BioinformaticsMicrobial GenomicsPeer-reviewedJan 27, 2021

Exact mapping of Illumina blind spots in the Mycobacterium tuberculosis genome reveals platform-wide and workflow-specific biases

Samuel J. Modlin, Cassidy Robinhold, Christopher Morrissey…·Faramarz Valafar

The paper identifies Illumina sequencing biases in M. tuberculosis genomes across seven workflows, revealing blind spots and proposing strategies to mitigate them.

43 citations

whole-genome sequencingstatistical model

𝕏 PostBluesky