Fate-mapping within human kidney organoids reveals conserved mammalian nephron progenitor lineage relationships.
Sara E Howden, Jessica M Vanslambrouck, Sean B Wilson, Ker Sin Tan, Melissa H Little
The paper uses human kidney organoids to study nephron progenitor lineage relationships, finding that SIX2+ cells contribute to nephron formation but not collecting duct epithelium, and their capacity declines over time.
bioRxiv · Oct 1, 2018 · PreprintCell Biology