A maternal-fetal PIEZO1 incompatibility as a barrier to Neanderthal-modern human admixture
Asya Makhro, Sebastian Bardh, Lars Kaestner, Isabel Dorn, Nicole Bender, Patrick Eppenberger
The paper identifies a maternal-fetal PIEZO1 incompatibility that likely restricted Neanderthal-modern human admixture by reducing fetal survival in hybrids.
bioRxiv · Sep 29, 2025 · PreprintEvolutionary Biology