Author

Seth B. Eddington

Southern Illinois University Carbondale

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:virus· 2 Assay:whole-genome sequencing· 2 Approach:biophysical modeling· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian A. Pater· 3 shared Christopher L. BarkauiD· 3 shared Keith T. GagnoniD· 3 shared Mansi Parasrampuria· 3 shared Michael S. Bosmeny· 3 shared Ramadevi Chilamkurthy· 3 shared Abadat O. Yinusa· 2 shared Adam A. White· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersGenomics

Adrian A. Pater

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Chemical control of 2'-hydroxyl-dependent Cas9 target engagement enables CRISPR RNA ribose replacement

Adrian A. Pater, Halle M. Barber, Sruthi Sudhakar, Ramadevi Chilamkurthy, Sunit Kumar Jana, Mansi Parasrampuria, Michael S. Bosmeny, Jacob A Graczyk-Marrs, Seth B. Eddington, Cole A Blazier, Leonora Abdullahu, Elise Malek-Adamian, Christopher L. Barkau, Daniel O’Reilly, Sergey Korolev, , Keith T. Gagnon

This study identifies the role of 2'-hydroxyl groups in crRNA for Cas9 DNA binding and develops chemically stabilized crRNAs with enhanced nuclease resistance and editing efficiency.

bioRxiv · Jan 26, 2026 · PreprintBiochemistry

High Throughput Nanopore Sequencing of SARS-CoV-2 Viral Genomes from Patient Samples

Adrian A. Pater, Michael S. Bosmeny, Mansi Parasrampuria, Seth B. Eddington, Katy N. Ovington, Adam A. White, Christopher L. Barkau, Paige E. Metz, Rourke J. Sylvain, Ramadevi Chilamkurthy, Abadat O. Yinusa, Scott W. Benzinger, Madison M. Hebert, Keith T. Gagnon

The paper provides protocols for high throughput sequencing of SARS-CoV-2 genomes using MinION and ARTIC primers, with applicable steps for other platforms.

Journal of Biological Methods · Sep 27, 2021Peer-reviewedGenomics

Emergence and Evolution of a Prevalent New SARS-CoV-2 Variant in the United States

Adrian A. Pater, Michael S. Bosmeny, Christopher L. Barkau, Katy N. Ovington, Ramadevi Chilamkurthy, Mansi Parasrampuria, Seth B. Eddington, Abadat O. Yinusa, Adam A. White, Paige E. Metz, Rourke J. Sylvain, Madison M. Hebert, Scott W. Benzinger, Koushik Sinha, Keith T. Gagnon

The paper identifies a new SARS-CoV-2 variant, 20C-US, that emerged in the U.S. in 2020 and became prevalent during the third pandemic wave.

bioRxiv · Jan 11, 2021 · PreprintGenomics