Seung Gu Park

Crowdsourcing: Spatial clustering of low-affinity binding sites amplifies in vivo transcription factor occupancy

The paper shows that spatial clustering of low-affinity TF binding sites increases their in vivo occupancy through cooperative effects, with tissue-specific scaling and motif-dependent impacts.

First intron length in mammals is associated with 5′ exon skipping rate

The paper investigates the relationship between first intron length and 5′ exon skipping rate in mammals, finding that 5′-biased exon skipping contributes to first intron elongation.