Author

Hiren Karathia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

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Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:statistical model· 1

Frequent Co-Authors

Sridhar Hannenhalli· 2 shared Boris Adryan· 1 shared Carl Kingsford· 1 shared Daphne Ezer· 1 shared Justin Malin· 1 shared Michelle Girvan· 1 shared Seung Gu Park· 1 shared Steve Mount· 1 shared

Activity by Year

2015-2015 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

Sridhar Hannenhalli

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2 papers

Recent·Most cited

A pathway-centric view of spatial proximity in the 3D nucleome across cell lines

Hiren Karathia, Carl Kingsford, Michelle Girvan, Sridhar Hannenhalli

The paper analyzes spatial proximity of genes in six human cell lines, finding context-specific pathway organization linked to gene function and pathway activity.

bioRxiv · Sep 17, 2015Bioinformatics

Crowdsourcing: Spatial clustering of low-affinity binding sites amplifies in vivo transcription factor occupancy

Justin Malin, Daphne Ezer, Xiaoyan Ma, Steve Mount, Hiren Karathia, Seung Gu Park, Boris Adryan, Sridhar Hannenhalli

The paper shows that spatial clustering of low-affinity TF binding sites increases their in vivo occupancy through cooperative effects, with tissue-specific scaling and motif-dependent impacts.

bioRxiv · Aug 12, 2015 · PreprintGenomics