NADPH oxidase inhibitor enhances brain resilience in Alzheimer's disease by reducing tauopathy and neuroinflammation
Jihyeon Lee, Seunghwan Sim, Yinglan Jin, Hyejun Park, Eun Young Byeon, Su Jin Kim, Sujin Yun, Hye‐Eun Lee, Da Un Jeong, Jung Min Suh, In Hye Lee, Ho‐Young Lee, Yongseok Choi, Yun Soo Bae
CRB-2131, an NADPH oxidase inhibitor, reduces tauopathy and neuroinflammation in Alzheimer's disease models, improving cognition and neuronal health.
bioRxiv · Mar 1, 2025 · PreprintNeuroscience