Cell cycle progression requires repression by Groucho during S-phase and its relief at G2-phase
Shaked Bar-Cohen, Ze’ev Paroush
This study shows Groucho represses e2f1 during S-phase and its phosphorylation by Cdk1 relieves this repression at G2-phase, preventing cell cycle arrest.
bioRxiv · Feb 22, 2022 · PreprintDevelopmental Biology