An Integrative Approach to Develop and Characterise Antibodies Against the Cancer Associated Antigen Sialyl Lewis A (CA 19-9)
Anika Freitag, Sana Khan Khilji, Ruslan Nedielkov, Shalini Murali Kumar, Michael Krummhaar, Janine Arndt, Gustavo Marçal Schmidt Garcia Moreira, Jost Lühle, Felix Goerdeler, Carsten Kamphues, María Andrea Mroginski, Christian Roth, Peter H. Seeberger, Heiko Michael Möller, Oren Moscovitz
This paper develops and characterizes novel monoclonal antibodies against sLeA, showing improved affinity and specificity compared to existing antibodies.
bioRxiv · Jun 15, 2025 · PreprintCancer Biology