The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin
Elena Grossi, Christie B. Nguyen, Saul Carcamo, Valentina Kirigin Callaú, Shannon Moran, Dan Filipescu, Somnath Tagore, Tessa M. Firestone, Michael‐Christopher Keogh, Lu Sun, Benjamin Izar, Dan Hasson, Emily Bernstein
The paper shows that the PBAF complex in melanoma facilitates REST occupancy at repressive chromatin, leading to upregulation of synaptic transcripts when ARID2 is mutated.
Molecular Cell · May 1, 2025Peer-reviewedMolecular Biology